Egyud and colleagues evaluated plasma levels of circulating tumor (ct)DNA in patients with esophageal adenocarcinoma, ranging from stage I to stage IV. The quantity of ctDNA and likelihood of ctDNA detection was greater at later stages, suggesting that it may be challenging to use for early-stage diagnosis.
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Cancer
August 23, 2019
August 22, 2019
In this multiinstitutional retrospective study, administration of adjuvant chemotherapy for patients with persistent nodal disease after induction therapy and esophagectomy was associated with improved survival.
August 22, 2019
This study of over 25,000 pts from the International Lung Cancer Consortium identified underweight and severly obese patients as having poorer survival than others, whereas a survival advantage was evident among patients who were overweight or mildly obese. Decreased BMI (wt loss) was associated with poorer outcomes across all BMI categories.
August 21, 2019
An interesting discussion in this manuscript of a case-control study of 666 subjects.
August 20, 2019
Interesting follow-up study of 208 pulmonary ground -glass opacities in 160 subjects, with a yield of three adenocardinomas.
August 15, 2019
Using a machine learning algorithm, resource utilization among more than 1 million Medicare patients undergoing one of 6 operations including CABG and lung resection was analyzed. Super users comprised 4.8% of the cohort but consumed 31.7% of the resources. Risk factors for super use included paraplegia/hemiplegia, weight loss, and CHF combined wit
August 15, 2019
Regionalization of care for complex problems remains an open question in most countries. This review demonstrated that, for high risk cancer operations in the US, the Leapfrog group's volume standards did not differentiate between surgical mortality outcomes for lung and esophageal cancer surgery.
August 8, 2019
A detailed and robust meta-analysis asserting lack of strong evidence supporting either modality.
August 8, 2019
Sridhar Rathinam of Glenfield Hospital in Leicester, United Kingdom, discusses surgical approaches for pulmonary neuroendocrine tumors.
August 5, 2019
Ng and colleagues evaluated 145 studies in order to provide evidence-based statements on the optimal approach for lobectomy for non–small cell lung cancer, comparing thoracotomy, multiport video-assisted thoracic surgery (VATS), robotic VATS, and uniportal VATS.