In this article, the authors review the main limitations of conventional randomized controlled trial designs, present basic concepts of statistical analysis, and highlight features of novel designs and how they may address some of the problems faced by previous trial designs.
ALERT!
This site is not optimized for Internet Explorer 8 (or older).
Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.
Cardiac
Challenges of Conventional and Novel Approaches to Clinical Trial Designs in Cardiovascular Medicine
March 20, 2025
March 20, 2025
In this video, the authors describe the surgical management of complex endocarditis that has spread to multiple cardiac chambers.
March 19, 2025
In this in-depth discussion, CTSNet Senior Editors Drs. Vince Gaudiani and Sameh Said examine the management of an anomalous right coronary artery.
March 19, 2025
This operative video demonstrates a valve-sparing aortic root replacement utilizing the reimplantation technique.
March 17, 2025
In this video, Dr. Vince Gaudiani demonstrates his technique for performing an upper ministernotomy.
March 14, 2025
At the 2024 EACTS Annual Meeting, Dr. Alice Copperwheat spoke with Kathryn Hewitt and Kathryn Gill about the role and utility of advanced clinical practitioners.
March 14, 2025
The authors present a 24-year-old patient referred to their institution with a diagnosis of endocarditis. Preoperative studies revealed an aorto-right atrial fistula, which was successfully resolved through surgery.
March 13, 2025
This week on The Beat, CTSNet Editor-in-Chief Joel Dunning examines how to prevent adverse publicity by patients on social media.
March 13, 2025
This study aimed to compare the clinical and echocardiographic long-term results of edge-to-edge (E-to-E) repair and neochordal repair, both associated with ring annuloplasty, for isolated anterior mitral leaflet lesions using propensity match analysis.
March 13, 2025
The VRECOVERY trial investigated the impact of virtual reality (VR) distraction therapy on postoperative pain, anxiety, and quality of recovery in patients undergoing coronary artery bypass grafting (CABG) surgery as a single-center randomized controlled trial. A total of 192 participants were allocated to either the intervention or control group.